Well Rinku,
Breast hypertrophy can be a real problem for some women. Reduction mammoplasty using various surgical techniques has become a more common treatment. Over the last 30 years about 32,000 such operations have been performed in Sweden, an average rate of about 25 per 100,000 women per year. That's about 12 a year in the average PCG, so a GP might see a case once every five years or so.
A new systematic review [1] pulls together the best available information. It informs about before and after symptoms, and is fascinating because this is one of those topics where randomised trials are rare as hen's teeth. So the question arises about dealing with different study architectures.
Systematic review
The authors [1] searched a variety of electronic databases for studies, using a number of different languages, and supplemented this with bibliographies and reviews. Studies that were case reports, abstracts, without outcomes of interest, with mixed procedures, in the setting of breast cancer, or with mixed genders, were not used. Those included had a minimum of 10 patients, were controlled trials, or case series, or historical or cross-sectional surveys, had a diagnosis of unilateral or bilateral breast hypertrophy or macromastia, used reduction mammoplasty and had clinical outcomes of interest.
The outcomes of interest were preoperative and postoperative reports of signs and symptoms and quality of life.
Results
Twenty-nine reports were included, with 4,200 women. Eighteen were observational studies, predominantly cross-sectional, and eleven were experimental studies, predominantly uncontrolled case series. The average age of women in the studies was about 36 years, with a wide range from 11 to 86 years. The average amount of breast tissue removed was about 1,500 grams from both breasts, with a range of 100 grams to 8,000 grams. Reduction was bilateral in over 90% of women. Observational and experimental studies had similar patient characteristics.
The frequency of reported symptoms before breast reduction was high (Table 1; Figure 1). Shoulder pain, and shoulder grooving caused by brassiere straps occurred in about 85% of women preoperatively, though back, neck and breast pain also occurred in over half of women before breast reduction, and intertrigo was also common. After the breast reduction the frequency of the symptoms reduced dramatically, and to about 10% on average
source site : http://www.medicine.ox.ac.uk/bandol ier/band89/b89-5.html
Answered by
Priyanka C
, an ibibo Master,
at
10:31 PM on September 09, 2008