* Vitamin A Acid (tretinoin, Retin-A, Renova). This ingredient, available by prescription, has the longest track record of success in treating aging skin and fine lines. Creams containing tretinoin must be used on an ongoing basis. They may produce redness and peeling at first, but discomfort can usually be minimized by lowering the cream's concentration or applying it less often until the skin gets used to it.
* Alpha-hydroxy acids. These so-called "fruit acids" include glycolic and lactic acid. Preparations containing these fruit acids are quite safe and cause no more than mild and temporary irritation. They produce only subtle improvement, though.
* Antioxidants. These include preparations that contain the vitamins A, C, and E, as well as beta-carotene. Such creams may provide a certain amount of sun protection as well as mild improvement of fine wrinkles.
* Ordinary moisturizers. Creams that don't contain any of the above substances can only make wrinkles look temporarily less prominent ("reduce the appearance of fine lines").


Source: http://www.medicinenet.com/wrinkles /page2.htm

Answered by sk , an ibibo Advisor, at 4:28 PM on October 16, 2008

The simplest method of skin treatment is the topical application of wrinkle creams. Widely available everywhere from pharmacies to health food stores, these creams are beneficial for the skin, helping to moisturize and nourish it. However, their ability to reduce wrinkles below the skin's surface is, unfortunately, very limited. In addition, any visible improvement may disappear when use of the topical agent is discontinued. Topical application of prescription drugs, most notably synthetic derivatives of Vitamin A (retinoids), can provide better results in improving sun-damaged and aging skin. Clinical studies of topical retinoid formulations find them to be safe and effective in diminishing fine wrinkles. However, most retinoids are skin irritants and often produce skin reactions.

Answered by Alok , an ibibo Master, at 2:33 PM on October 16, 2008

Topical application of prescription drugs, most notably synthetic derivatives of Vitamin A (retinoids), can improve the appearance of sun-damaged and aging skin.

For instance, topicals can be effective in diminishing fine wrinkles.

However, most tretinoins are skin irritants and often produce skin reactions.

In addition, any visible improvement may disappear when use of the drug is discontinued.

Answered by Seema , an ibibo Master, at 1:50 PM on October 16, 2008